Born equal: dual safeguards for daughter cell size symmetry.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23870117.
- Also identified by DOI 10.1016/j.cell.2013.06.035.
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Abstract
Development and homeostasis require repeated symmetric cell divisions, which in turn depend on a centered mitotic spindle. In this issue, Kiyomitsu and Cheeseman uncover two mechanisms that ensure correct spindle positioning in anaphase: cortical dynein for pulling the spindle to the cell center and asymmetric membrane elongation that adjusts the position of the cell center to the cleavage plane.
Medical subject headings
- Anaphase
- Cell Membrane
- Dyneins
- Spindle Apparatus