Adrenal adenoma with excess secretion of corticosterone and 18-hydroxycorticosterone.

Morioka, M; Sen, Y; Inoue, K; Fujita, Y · J Urol · 1990

case_report · Level V

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Abstract

A 64-year-old man with sudden onset of quadriplegia due to marked hypokalemia was referred to our clinic with suppressed plasma renin activity in the presence of a low aldosterone level. Computerized tomography demonstrated a left adrenal adenoma, shown on adrenal scintigraphy to be functioning. The elevated basal level of plasma corticosterone and its increased response to 1-24 adrenocorticotropic hormone suggested the tumor produced corticosterone. The surgical specimen was a benign adrenocortical adenoma with excess content of corticosterone and 18-hydroxycorticosterone.

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