Alzheimer's disease: From big data to mechanism.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23883924.
- Also identified by DOI 10.1038/nature12457 and PMC identifier 4409124.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The gene variant <i>APOE4</i> is the most common genetic risk factor associated with late-onset Alzheimer’s disease. A comprehensive, multilayer study reveals the molecular and cellular signatures of <i>APOE4</i> in humans.
Medical subject headings
- Alzheimer Disease
- Apolipoprotein E4
- Genome, Human
- Genomics