Can we do better than dobutamine?
Level V
Where this comes from
- Record sourced from PubMed, PMID 23908327.
- Also identified by DOI 10.1161/CIRCRESAHA.113.302000 and PMC identifier 3869564.
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Abstract
The development of dobutamine, an infusible inotropic drug for heart failure, was first described in 1975. Although this sympathomimetic was designed to increase cardiac output, it is far from ideal as a longterm safe strategy. New drugs for acute heart failure are needed, and to develop new approaches will require diverse expertise and resources.
Medical subject headings
- Cardiotonic Agents
- Dobutamine
- Drug Discovery
- Heart Failure