ENCODE and a new landscape for psychiatric genetics.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 23908338.
- Also identified by DOI 10.1192/bjp.bp.113.127191.
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Abstract
Despite rigorous research into the genetics of neuropsychiatric disorders, the mechanism by which polygenic risk leads to complex clinical phenotypes remains unclear. The Encyclopedia of DNA Elements (ENCODE) project gives us new insight into gene regulation, and gene-gene and gene-environment interaction. Better understanding of these key genomic mechanisms may provide the answers we have been searching for.
Medical subject headings
- Databases, Genetic
- Mental Disorders