On your (methyl) mark, get TET1, go!
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 23910076.
- Also identified by DOI 10.1016/j.stem.2013.07.011.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Tet proteins and DNA demethylation are key regulators of embryonic stem cells, but their roles in development and tissue stem cells remain unclear. In this issue, Zhang et al. (2013) show that Tet1 regulates adult hippocampal neurogenesis by controlling progenitor proliferation, and Tet1 deficiency generates defects in learning and memory.
Medical subject headings
- Aging
- Cognition
- DNA-Binding Proteins
- Hippocampus
- Neurogenesis
- Proto-Oncogene Proteins