Transplantable liver organoids made from only three ingredients.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23910079.
- Also identified by DOI 10.1016/j.stem.2013.07.014 and PMC identifier 3828077.
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Abstract
Liver cell therapies using induced pluripotent stem cells (iPSCs) are in development. A recent paper in Nature by Takebe et al. expands the range of liver diseases that could be treated with iPSC-derived hepatocytes by combining them with endothelial and stromal cells to generate organoids that survive and function extrahepatically.
Medical subject headings
- Induced Pluripotent Stem Cells
- Liver
- Regenerative Medicine