Statistical mechanics of pluripotency.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23911316.
- Also identified by DOI 10.1016/j.cell.2013.07.024.
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Abstract
Recent reports using single-cell profiling have indicated a remarkably dynamic view of pluripotent stem cell identity. Here, we argue that the pluripotent state is not well defined at the single-cell level but rather is a statistical property of stem cell populations, amenable to analysis using the tools of statistical mechanics and information theory.
Medical subject headings
- Pluripotent Stem Cells