Directing self-assembly of DNA nanotubes using programmable seeds.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23919535.
- Also identified by DOI 10.1021/nl400881w.
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Abstract
Control over when and where nanostructures arise is essential for the self-assembly of dynamic or multicomponent devices. We design and construct a DNA origami seed for the control of DAE-E tile DNA nanotube assembly. Seeds greatly accelerate nanotube nucleation and growth because they serve as nanotube nucleation templates. Seeds also control nanotube circumference. Simulations predict nanotube growth rates and suggest a small nucleation barrier remains when nanotubes grow from seeds.
Medical subject headings
- DNA
- Nanostructures
- Nanotubes