Genetic and antigenic characterization of enterovirus 71 in Ho Chi Minh City, Vietnam, 2011.
Where this comes from
- Record sourced from PubMed, PMID 23922846.
- Also identified by DOI 10.1371/journal.pone.0069895 and PMC identifier 3726754.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam.
Medical subject headings
- Antigens, Viral
- Enterovirus