nCal: an R package for non-linear calibration.
Where this comes from
- Record sourced from PubMed, PMID 23926226.
- Also identified by DOI 10.1093/bioinformatics/btt456 and PMC identifier 3789552.
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Abstract
Non-linear calibration is a widely used method for quantifying biomarkers wherein concentration-response curves estimated using samples of known concentrations are used to predict the biomarker concentrations in the samples of interest. The R package nCal fills an important gap in the open source, stand-alone software for performing non-linear calibration. For curve fitting, nCal provides a new implementation of a robust, Bayesian hierarchical five-parameter logistic model. nCal supports a simple graphical user interface that can be used by laboratory scientists, and contains functionality for importing data from the multiplex bead array assay instrumentation. The R package 'nCal' is available from http://cran.r-project.org/web/packages/nCal/ under GPL-2 or later.
Medical subject headings
- Nonlinear Dynamics