Early hits and long-term consequences: tracking the lasting impact of prenatal smoke exposure on telomere length in children.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 23927510.
- Also identified by DOI 10.2105/AJPH.2012.301208 and PMC identifier 3786752.
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Abstract
We examined the association between telomere length and prenatal tobacco exposure (PTE) in 104 children aged 4 to 14 years. Salivary telomere length (STL) was determined from salivary DNA using quantitative polymerase chain reaction. Of the children, 18% had maternal reported PTE. Mean STL was significantly lower among children with PTE (6.4 vs 7.5, P < .05). Findings extend the literature demonstrating the negative long-term effects of PTE to include a cellular marker of aging linked to multiple negative health outcomes.
Medical subject headings
- Maternal Exposure
- Prenatal Exposure Delayed Effects
- Telomere
- Tobacco Smoke Pollution