Association between obesity and postoperative atrial fibrillation in patients undergoing cardiac operations: a systematic review and meta-analysis.

Hernandez, Adrian V; Kaw, Roop; Pasupuleti, Vinay; Bina, Pouya; Ioannidis, John P A; Bueno, Hector; Boersma, Eric; Gillinov, Marc et al. · Ann Thorac Surg · 2013

meta_analysis · Level I

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Abstract

In a systematic review and random-effects meta-analysis, we evaluated whether obesity is associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac operations. We selected 18 observational studies until December 2011 that excluded patients with preoperative AF (n=36,147). Obese patients had a modest higher risk of POAF compared with nonobese (odds ratio, 1.12; 95% confidence interval, 1.04 to 1.21; p=0.002). The association between obesity and POAF did not vary substantially by type of cardiac operation, study design, or year of publication. POAF was significantly associated with a higher risk of stroke, respiratory failure, and operative death.

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