Impact of colonization pressure and strain type on methicillin-resistant Staphylococcus aureus transmission in children.

Popoola, Victor O; Carroll, Karen C; Ross, Tracy; Reich, Nicholas G; Perl, Trish M; Milstone, Aaron M · Clin Infect Dis · 2013

prospective_cohort · Level II

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Abstract

We studied the transmissibility of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and healthcare-associated methicillin-resistant S. aureus (HA-MRSA) strains and the association of MRSA colonization pressure and MRSA transmission in critically ill children. Importantly, we found that in hospitalized children MRSA colonization pressure above 10% increases the risk of MRSA transmission 3-fold, and CA-MRSA and HA-MRSA strains have similar transmission dynamics.

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