Electrokinetic tweezing: three-dimensional manipulation of microparticles by real-time imaging and flow control.

Cummins, Zachary; Probst, Roland; Shapiro, Benjamin · Lab Chip · 2013

basic_science · Level V

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Abstract

Electrokinetic tweezing in three dimensions is achieved for the first time using a multi-layer microfluidic device, a model-based control algorithm, and a 3D imaging algorithm connected in a feedback loop. Here we demonstrate steering of microparticles along 3D trajectories and trapping in all three dimensions with accuracy as good as 1 μm.