Pattern recognition analysis of anterior cingulate cortex blood flow to classify depression polarity.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 23969484.
- Also identified by DOI 10.1192/bjp.bp.112.122838 and PMC identifier 3787302.
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Abstract
Differentiating bipolar from recurrent unipolar depression is a major clinical challenge. In 18 healthy females and 36 females in a depressive episode--18 with bipolar disorder type I, 18 with recurrent unipolar depression--we applied pattern recognition analysis using subdivisions of anterior cingulate cortex (ACC) blood flow at rest, measured with arterial spin labelling. Subgenual ACC blood flow classified unipolar v. bipolar depression with 81% accuracy (83% sensitivity, 78% specificity).
Medical subject headings
- Bipolar Disorder
- Depressive Disorder
- Gyrus Cinguli