A novel approach to quantifying ciliary physiology: microfluidic mixing driven by a ciliated biological surface.

Jonas, Stephan; Zhou, Elaine; Deniz, Engin; Huang, Brendan; Chandrasekera, Kenny; Bhattacharya, Dipankan; Wu, Yu; Fan, Rong et al. · Lab Chip · 2013

basic_science · Level V

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Abstract

From the lungs to the central nervous system, cilia-driven fluid flow plays a fundamental role in many facets of life. Yet, there are few quantitative methods for analysing the function of ciliated surfaces. Here, we report a novel microfluidic approach for quantifying the performance of a ciliated surface using mixing performance as an integrated readout.

Medical subject headings