A Central role for mTOR in lipid homeostasis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23973332.
- Also identified by DOI 10.1016/j.cmet.2013.08.002 and PMC identifier 3818790.
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Abstract
The mechanistic target of rapamycin (mTOR) signaling pathway regulates many fundamental metabolic and physiological processes, including lipid metabolism. We explore recent findings on the role of mTOR in lipid homeostasis, with an emphasis on recent findings from in vivo models regarding the role of mTORC2 in lipolysis, lipogenesis, and adipogenesis.
Medical subject headings
- Lipid Metabolism
- TOR Serine-Threonine Kinases