Biochemical and physical signal gradients in hydrogels to control stem cell behavior.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23983019.
- Also identified by DOI 10.1002/adma.201302364 and PMC identifier 3863582.
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Abstract
Three-dimensional (3D) gradients of biochemical and physical signals in macroscale degradable hydrogels are engineered that can regulate photoencapsulated human mesenchymal stem cell (hMSC) behavior. This simple, cytocompatible, and versatile gradient system may be a valuable tool for researchers in biomaterials science to control stem cell fate in 3D and guide tissue regeneration.
Medical subject headings
- Biocompatible Materials
- Hydrogels
- Mesenchymal Stem Cells