Peptide amphiphile nanoparticles enhance the immune response against a CpG-adjuvanted influenza antigen.

Zope, Harshal; Quer, Christophe Barnier; Bomans, Paul H H; Sommerdijk, Nico A J M; Kros, Alexander; Jiskoot, Wim · Adv Healthc Mater · 2014

basic_science · Level V

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Abstract

Cationic peptide amphiphile nanoparticles are employed for co-delivery of immune modulator CpG and antigen. This results in better targeting to the antigen presenting cells and eliciting strong Th1 response, which is effective against the intracellular pathogens.

Medical subject headings