Cortical folding is altered before surgery in infants with congenital heart disease.
Where this comes from
- Record sourced from PubMed, PMID 23988135.
- Also identified by DOI 10.1016/j.jpeds.2013.06.045 and PMC identifier 3905308.
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Abstract
Infants with congenital heart disease have altered brain development. We characterized cortical folding, a critical part of brain development, in congenital heart disease infants and demonstrated an overall decrease in cortical surface area and cortical folding with regional alterations in the right lateral sulcus and left orbitofrontal region, cingulate region, and central sulcus. These abnormalities were present prior to surgery.
Medical subject headings
- Cerebral Cortex
- Heart Defects, Congenital