Breast cancer bone metastases: it's all about the neighborhood.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 23993088.
- Also identified by DOI 10.1016/j.cell.2013.08.020.
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Abstract
In order to establish themselves in distal sites, metastatic cancer cells need to acquire organ-specific traits. Zhang et al. provide evidence in breast cancer that a tumor cell's acquisition of properties for successful bone metastasis is influenced by signals from the stroma of the primary tumor.
Medical subject headings
- Bone Neoplasms
- Breast Neoplasms
- Neoplasm Metastasis
- Signal Transduction