The role of elective pelvic radiotherapy in clinically node-negative prostate cancer: a systematic review.

Dirix, Piet; Joniau, Steven; Van den Bergh, Laura; Isebaert, Sofie; Oyen, Raymond; Deroose, Christophe M; Lerut, Evelyne; Haustermans, Karin · Radiother Oncol · 2014

systematic_review · Level I

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Abstract

The role of elective radiotherapy of the pelvic nodal regions in clinically node-negative prostate cancer patients remains highly controversial. This review will address the difficulty of non-invasive nodal staging, even with more advanced imaging techniques, and will show that surgical staging still finds a relatively high percentage of patients with intermediate- or high-risk prostate cancer that have microscopic tumor invasion in the pelvic nodes. Finally, an overview of the current literature on elective pelvic irradiation will be provided.

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