Meta-analysis of patients taking statins before revascularization and aortic valve surgery.
meta_analysis · Level I
Where this comes from
- Record sourced from PubMed, PMID 23993896.
- Also identified by DOI 10.1016/j.athoracsur.2013.04.096.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Statin intake before cardiac surgery is associated with favorable outcomes. We sought to analyze the evidence for statin pretreatment before isolated coronary artery bypass graft surgery and aortic valve replacement surgery. In this meta-analysis, we demonstrate beneficial results for the endpoints mortality, stroke, atrial fibrillation, and length of stay in hospital in 36,053 statin-pretreated coronary artery bypass graft surgery patients compared with control subjects retrieved from 32 studies, but fail to detect relevant advantages through preoperative statin therapy for 3,091 patients undergoing aortic valve replacement from four trials. Strict adherence to guidelines recommending statin treatment before CABG surgery is therefore mandatory.
Medical subject headings
- Aortic Valve
- Coronary Artery Bypass
- Heart Valve Prosthesis Implantation
- Hydroxymethylglutaryl-CoA Reductase Inhibitors