Cell-laden microengineered and mechanically tunable hybrid hydrogels of gelatin and graphene oxide.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23996513.
- Also identified by DOI 10.1002/adma.201301082 and PMC identifier 3898458.
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Abstract
Incorporating graphene oxide inside GelMA hydrogels enhances their mechanical properties and reduces UV-induced cell damage while preserving their favorable characteristics for 3D cell encapsulation. NIH-3T3 fibroblasts encapsulated in GO-GelMA microgels demonstrate excellent cellular viability, proliferation, spreading, and alignment. GO reinforcement combined with a multi-stacking approach offers a facile engineering strategy for the construction of complex artificial tissues.
Medical subject headings
- Gelatin
- Graphite
- Hydrogels