A general strategy for dual-triggered combined tumor therapy based on template semi-graphitized mesoporous silica nanoparticles.
basic_science · Level V
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- Record sourced from PubMed, PMID 23997032.
- Also identified by DOI 10.1002/adhm.201300324.
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Abstract
A general strategy is developed for dual-triggered chemo-photothermal tumor therapy based on template semi-graphitized mesoporous silica nanoparticles (TsGMSN). The strategy endues classic MSN with new charming properties, while easily escaping from toxicity of the surfactant. The doxorubicin-loaded system (TsGMSND) exhibits synergistic heat-stimulative, pH-responsive, and sustained release, and effective combined tumor therapy.
Medical subject headings
- Antineoplastic Agents
- Hyperthermia, Induced
- Nanoparticles
- Photochemotherapy
- Silicon Dioxide