Mrap2: an accessory protein linked to obesity.

Liu, Tiemin; Elmquist, Joel K; Williams, Kevin W · Cell Metab · 2013

other · Level V

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Abstract

Melanocortin receptors are critical modulators of energy balance and glucose homeostasis. Companion studies published in Science (Asai et al., 2013; Sebag et al., 2013) establish a role for melanocortin receptor accessory protein 2 (Mrap2) in regulating melanocortin receptor activity and in the development of obesity in zebrafish, rodents, and humans.

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