Cyclical caspofungin for chronic pulmonary aspergillosis in sarcoidosis.

Keir, Gregory J; Garfield, Benjamin; Hansell, David M; Loebinger, Michael R; Wilson, Robert; Renzoni, Elisabetta A; Wells, Athol U; Maher, Toby M · Thorax · 2014

case_series · Level IV

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Abstract

In sarcoidosis, chronic pulmonary aspergillosis (CPA) may be associated with significant morbidity, and treatment failure rates are often high, even with newer triazole antifungal agents. We report a treatment regimen of cyclical caspofungin infusions in 10 patients with sarcoidosis and worsening CPA despite oral triazoles.

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