Jumonji and cardiac fate.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24030015.
- Also identified by DOI 10.1161/CIRCRESAHA.113.302202 and PMC identifier 3974910.
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Abstract
Considerable information is known about the extracellular signals that drive pluripotent stem cells through a stepwise program to become cardiomyocytes. A paper by Ohtani <i>et al</i>. in this issue now links extrinsic signals to histone demethylation needed to form mesoderm, the first step in cardiogenesis.
Medical subject headings
- Cell Differentiation
- Embryonic Stem Cells
- Endothelium, Vascular
- Jumonji Domain-Containing Histone Demethylases
- Mesoderm
- Myocytes, Cardiac