Comment on "Influence of HLA-C expression level on HIV control".
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24031002.
- Also identified by DOI 10.1126/science.1241266.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Apps et al. (Reports, 5 April 2013, p. 87) found that high human leukocyte antigen C (HLA-C) expression favors HIV-1 control. However, as noted here, HLA-C was assessed with a monoclonal antibody (DT9) that cross-reacts with HLA-E. In the context of the available evidence, this is consistent with the idea that the two leukocyte antigens collaborate to keep the HIV-1 virus at bay.
Medical subject headings
- Gene Expression Regulation
- HIV
- HIV Infections
- HLA-C Antigens
- T-Lymphocytes, Cytotoxic