Efficacy of combined antidepressant therapy in resistant neurotic disorder.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 2404536.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A 35-year-old woman with persistent affective and phobic symptoms responded dramatically to a combination of isocarboxazid and amitriptyline, and this improvement was maintained over the next three-and-a-half years. Isocarboxazid was replaced by placebo, using double-blind procedure. The change to placebo was accompanied by a marked increase in anxiety and depressive symptoms, which resolved when active isocarboxazid was reintroduced. It is suggested that combined antidepressant therapy still has a place in the treatment of resistant neurotic disorder.
Medical subject headings
- Amitriptyline
- Anxiety Disorders
- Depressive Disorder
- Isocarboxazid
- Obsessive-Compulsive Disorder
- Phobic Disorders