Treatment of Alzheimer's disease with short- and long-term oral THA and lecithin: a double-blind study.
Level II
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Abstract
Ten Alzheimer's disease patients underwent a trial of oral tetrahydroaminoacridine (THA) and lecithin. After 3 inpatient weeks there was no clear therapeutic effect. Three of six patients able to continue in long-term treatment showed measurable cognitive improvement, but only one displayed clinically obvious improvement.
Medical subject headings
- Alzheimer Disease
- Aminoacridines
- Phosphatidylcholines
- Tacrine