Comment on "Community-wide isoniazid preventive therapy drives drug-resistant tuberculosis: a model-based analysis".
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24068733.
- Also identified by DOI 10.1126/scitranslmed.3006386.
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Abstract
Mills et al. recently used mathematical modeling to show that community-wide isoniazid preventative therapy may lead to a long-term increase in resistance at the population level. Although community-wide isoniazid preventive therapy may be useful in preventing tuberculosis (TB) in low-TB/HIV settings, isoniazid resistance is especially of concern in high TB/HIV populations.
Medical subject headings
- Antitubercular Agents
- Isoniazid
- Tuberculosis