The western immunoblot procedure for HIV antibodies and its interpretation.

Dodd, R Y; Fang, C T · Arch Pathol Lab Med · 1990

review · Level V

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Abstract

The Western blot is frequently used to confirm human immunodeficiency virus type 1 (HIV-1) screening tests as it permits the identification of antibodies to individual component polypeptides of HIV-1. The procedure is described and different criteria for evaluation of HIV-1 Western blots are compared. The significance and management of indeterminate blot patterns are discussed.

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