Cerebral organoids in a dish: progress and prospects.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24074857.
- Also identified by DOI 10.1016/j.cell.2013.09.010 and PMC identifier 5127703.
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Abstract
A three-dimensional culture of cortical tissues derived from pluripotent stem cells offers an opportunity to model human brain development and disorders. In a recent issue of Nature, Lancaster et al. describe a new method for generating cerebral organoids in a dish and use it to model microcephaly.
Medical subject headings
- Brain
- Microcephaly
- Models, Biological
- Organoids
- Tissue Culture Techniques