Three-dimensional reconstruction identifies misaligned pulmonary veins as intrapulmonary shunt vessels in alveolar capillary dysplasia.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 24079727.
- Also identified by DOI 10.1016/j.jpeds.2013.08.035 and PMC identifier 3994558.
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Abstract
Alveolar capillary dysplasia (ACD) with misalignment of pulmonary veins (MPV) is a lethal neonatal lung disease. Death from ACD/MPV is caused by hypoxia, but the role of the MPV is unknown. Using 3-dimensional reconstruction of ACD/MPV lung tissue, we report that the veins in MPV are intrapulmonary shunt vessels, and speculate that MPV contributes to the poor prognosis.
Medical subject headings
- Imaging, Three-Dimensional
- Immunohistochemistry
- Lung
- Persistent Fetal Circulation Syndrome
- Pulmonary Alveoli
- Pulmonary Veins