Comment: infection antedating autoimmunity-- shared mechanisms in the brain?
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 24089387.
- Also identified by DOI 10.1212/WNL.0b013e3182a9f58b.
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Abstract
Anti-NMDA receptor (NMDAR) encephalitis is a well-recognized immunotherapy-responsive condition, often diagnosed in younger individuals with characteristic clinical symptoms. In women, ovarian teratomas are frequently found and thought to trigger the antibody response against the NMDAR by ectopically expressing neuronal antigens. The present study describes the case of a patient with HSV encephalitis (HSVE) who develops a second episode of neurologic abnormalities, which is in fact NMDAR encephalitis.(1.)
Medical subject headings
- Anti-N-Methyl-D-Aspartate Receptor Encephalitis
- Autoimmunity
- Brain
- Encephalitis, Viral