What's the Mtrr with your grandparents?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24093670.
- Also identified by DOI 10.1016/j.cmet.2013.09.016 and PMC identifier 3947785.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Reduced folate levels can cause developmental defects and megaloblastic anemia. Padmanabhan et al. (2013) show that mutation in mice of a folate metabolism gene, Mtrr, which encodes for methionine synthase reductase, causes developmental defects not only in the mutant progeny, but also in genetically wild-type descendants for up to four generations.
Medical subject headings
- Congenital Abnormalities
- Embryo, Mammalian
- Epigenesis, Genetic
- Ferredoxin-NADP Reductase
- Fetal Growth Retardation
- Folic Acid