Hedonic and homeostatic overlap following fat ingestion.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24093671.
- Also identified by DOI 10.1016/j.cmet.2013.09.012 and PMC identifier 3869225.
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Abstract
Ingestion of fatty foods increases dopamine release in the substantia nigra, producing a positive hedonic state. Tellez et al. (2013) demonstrate that an intestinal signal generated by fat consumption, oleoylethanolamide, stimulates central dopamine activity, thus regulating the reward value of fat and establishing a link between caloric-homeostatic and hedonic-homeostatic controllers.
Medical subject headings
- Corpus Striatum
- Dietary Fats
- Dopamine
- Endocannabinoids
- Ethanolamines
- Gastrointestinal Tract
- Oleic Acids