Regional specificity in the Drosophila midgut: setting boundaries with stem cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24094316.
- Also identified by DOI 10.1016/j.stem.2013.09.008 and PMC identifier 3897550.
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Abstract
Many organs consist of distinct subregions with specialized physiological roles, but how regional boundaries are upheld during cellular renewal is largely unknown. Recently, Buchon et al. (2013) and Marianes and Spradling (2013) showed that subregions of the Drosophila midgut are maintained by patterned transcription factors and compartmentalized stem cell progeny.
Medical subject headings
- Drosophila
- Intestines