Build-a-brain.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24094317.
- Also identified by DOI 10.1016/j.stem.2013.09.010.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A major barrier in understanding nervous system development is modeling the cellular interactions that form the human brain. Recently, in the journal Nature, Lancaster et al. (2013) established a protocol for culturing pluripotent stem cell (PSC)-derived "cerebral organoids" that mimics the developing human brain's cellular organization, segregates into distinct brain regions, and models microcephaly.
Medical subject headings
- Brain
- Microcephaly
- Models, Biological
- Organoids
- Tissue Culture Techniques