Toward the development of a global induced pluripotent stem cell library.

Turner, Marc; Leslie, Stephen; Martin, Nicholas G; Peschanski, Marc; Rao, Mahendra; Taylor, Craig J; Trounson, Alan; Turner, David et al. · Cell Stem Cell · 2013

basic_science · Level V

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Abstract

The ability to preselect the donor genotype of iPSC lines provides important opportunities for immune matching in cell therapy. Here we propose that an international assessment should be made of how immune incompatibility can best be managed and how a network of GMP HLA homozygous haplobanks could be operated.

Medical subject headings