pLogo: a probabilistic approach to visualizing sequence motifs.
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- Record sourced from PubMed, PMID 24097270.
- Also identified by DOI 10.1038/nmeth.2646.
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Abstract
Methods for visualizing protein or nucleic acid motifs have traditionally relied upon residue frequencies to graphically scale character heights. We describe the pLogo, a motif visualization in which residue heights are scaled relative to their statistical significance. A pLogo generation tool is publicly available at http://plogo.uconn.edu/ and supports real-time conditional probability calculations and visualizations.
Medical subject headings
- Nucleic Acids
- Proteins
- Sequence Alignment
- Sequence Analysis, Protein