Therapeutically reeducating macrophages to treat GBM.

Garris, Christopher; Pittet, Mikael J · Nat Med · 2013

editorial · Level V

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Abstract

Glioblastoma multiforme (GBM) is the most common type of aggressive malignant brain cancer. The current lack of successful therapeutics means that this disease has a dismal prognosis. However, a new study in mice offers hope for patients with GBM by demonstrating the efficacy of a novel drug that targets GBM-associated macrophages (pages 1264–1272).

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