NKT cells: the smoking gun in fungal-induced asthma?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24100979.
- Also identified by DOI 10.1038/nm.3360.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Aspergillus fumigatus is a fungus that is associated with a severe form of asthma, although the precise immunological basis for this disease is unclear. A new study in mice shows that natural killer T (NKT) cells are crucial for progression of A. fumigatus–induced asthma and also identifies a glycolipid antigen from this fungus that seems to drive this NKT cell–mediated inflammatory response (pages 1297–1304).
Medical subject headings
- Aspergillus fumigatus
- Bronchial Hyperreactivity
- Glycosphingolipids
- Natural Killer T-Cells