SAX-7 and menorin light the path for dendrite morphogenesis.
basic_science · Level V
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- Record sourced from PubMed, PMID 24120127.
- Also identified by DOI 10.1016/j.cell.2013.09.029.
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Abstract
Environmental and cellular cues pattern dendritic growth and direct dendrites to their targets. However, little is known about the signals regulating interactions with the surrounding substrate. Dong et al. and Salzberg et al. now identify a tripartite ligand-receptor complex that conveys cues from the substrate necessary for the patterning of complex dendrites in C. elegans.
Medical subject headings
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Dendrites
- Membrane Proteins
- Neural Cell Adhesion Molecules
- Neurogenesis
- Neurons