Primary cutaneous amyloidosis of the glans penis. Two case reports and a review of the literature.

Abstract

Primary cutaneous amyloidosis of the penis is a rare entity. We describe two cases of primary penile cutaneous amyloidosis presenting as localized lesions on the penis and not associated with systemic amyloidosis. A comprehensive literature review of all published cases. The rarest form of cutaneous amyloidosis, nodular amyloidosis, is the most frequent presentation of penis-limited cutaneous amyloid with a low incidence of systemic disease progression. Although primary nodular amyloidosis is a rare entity it seems to be the most frequent presentation of penile-limited cutaneous disease, with a low incidence of systemic involvement.