The roles of TGFβ in the tumour microenvironment.

Pickup, Michael; Novitskiy, Sergey; Moses, Harold L · Nat Rev Cancer · 2013

review · Level V

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Abstract

The influence of the microenvironment on tumour progression is becoming clearer. In this Review we address the role of an essential signalling pathway, that of transforming growth factor-β, in the regulation of components of the tumour microenvironment and how this contributes to tumour progression.

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