Going with the flow: from circulating tumor cells to DNA.
Level V
Where this comes from
- Record sourced from PubMed, PMID 24132635.
- Also identified by DOI 10.1126/scitranslmed.3006305.
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Abstract
Molecular analyses of circulating tumor DNA (ctDNA) in plasma from cancer patients have the potential to deliver minimally invasive diagnostic and disease-monitoring biomarkers. Drawing from experience gained through the translation of circulating tumor cell detection to clinical tests, we discuss ctDNA as a source of tumor material for biomarker development.
Medical subject headings
- DNA, Neoplasm
- Neoplastic Cells, Circulating