Intravoxel incoherent motion imaging of masticatory muscles: pilot study for the assessment of perfusion and diffusion during clenching.

Abstract

The purpose of this study was to evaluate intravoxel incoherent motion (IVIM) imaging for assessing perfusion and diffusion of masticatory muscles during clenching. A prospective study was performed to assess the perfusion and diffusion of masticatory muscles during clenching. The masseter and medial pterygoid muscles participate in clenching, and the lateral pterygoids do not. IVIM parameters (microvascular volume fraction, f; pure diffusion coefficient, D; and perfusion-related incoherent microcirculation, D*) were determined on both the clenching and the balancing sides in 24 volunteers. The Wilcoxon test was used to compare the IVIM parameters at rest and during clenching. The f and D* values of the masseters significantly increased on the clenching side (f = 0.17 ± 0.10 vs 0.29 ± 0.11, p < 0.001; D* = 21.3 ± 18.5 × 10(-3) mm(2)/s vs 42.1 ± 33.3 × 10(-3) mm(2)/s, p = 0.0008). However, the D values did not change during clenching (1.26 ± 0.23 × 10(-3) mm(2) vs 1.21 ± 0.35 × 10(-3) mm(2)). The f values of the medial pterygoids also increased on the clenching side (0.20 ± 0.09 vs 0.30 ± 0.09, p < 0.001). On the balancing side, the f values of the masseters (0.19 ± 0.12 vs 0.30 ± 0.12, p < 0.001) and medial pterygoids (0.20 ± 0.09 vs 0.29 ± 0.11, p = 0.0007) significantly increased during clenching. In contrast, the IVIM values of the lateral pterygoids did not change. IVIM imaging may be useful for assessing perfusion and diffusion of the masticatory muscles.